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Fibroadenoma
Image 1 (Ultrasound): Within the upper outer quadrant of the left breast
at the 2 o'clock position is a well circumscribed, ovoid hypoechoic lesion
measuring 137mm maximally. No contained calcification or vascularity is identified.
The appearance is consistent with, but not diagnostic of, a fibroadenoma.
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Fibroadenoma Image 2 (H&E, x2.5): Histological section of a fibroadenoma showing
compressed ducts (intra-canalicular growth pattern) surrounded by mild and
bland stromal hypercellularity. The ducts are lined by a dual population of
uniform epithelial and myoepithelial cells. |
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Breast Carcinoma
Image 3a (Mammogram, right breast): A non-calcified 22mm mass is present
in the upper inner quadrant of the right breast.
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Image 3b (Ultrasound, right breast): Ultrasound of the same lesion showed
an ill-defined solid mass with irregular margins, distortion of adjacent
stroma and posterior acoustic shadowing, features which are suspicious for
malignancy. Biopsy confirmed an invasive ductal carcinoma. |
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Breast Carcinoma Image 4a: Mastectomy showing an irregular pale tumour (arrow) with surrounding fibrosis
consistent with a breast carcinoma. |
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Image 4b (H&E, x2.5): Histological section of a moderately
differentiated (Grade 2) invasive ductal carcinoma, type not otherwise
specified, infiltrating through the breast parenchyma and surrounded by
desmoplastic stroma. Occasional poorly formed tubules can be seen at the
periphery (arrows). |
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Breast Carcinoma
Image 5 (H&E, x10): Histological section of a typical invasive lobular
carcinoma showing the classical alignment of single cells in rows.
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Pathology
images courtesy of PathWest Laboratory Medicine.