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Diagnostic Imaging Pathways - Multiple Myeloma

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Magnetic Resonance Imaging

  • Highly sensitive modality for the detection of myeloma-related bone lesions. Allows visualisation and assessment of the degree of malignant infiltration of the medullary cavity. It can effectively distinguish benign and malignant compression fractures. 9
  • MRI is also the modality of choice for suspected cord compression. 9
  • In comparison to the conventional skeletal survey and MDCT, MRI demonstrates higher sensitivity for the detection of bone lesions. 13,17
  • According to current guidelines, MRI should be considered in symptomatic patients with a negative skeletal survey. 9 Whole body MRI is preferable, however, MRI of the spine and pelvis is also helpful if resources are limited.
  • In patients with apparent solitary plasmacytoma on skeletal survey, MRI of the spine should be performed to exclude occult lesions. 9

 


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