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Graves' Disease Image 1a and 1b (Thyroid Scintigraphy - Tc99m Pertechnetate): The thyroid gland has taken up 6.3% of the administered dose (normal between 0.6-2.7%). This is evenly distributed throughout both lobes of the thyroid gland. No focal abnormalities are demonstrated. The appearances are typical of Graves' Disease. |
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Image 2 (H&E, x10): Histological section of Graves' disease showing hyperplastic follicles with infolding of the follicular epithelium to form papillary projections (blue arrow). The colloid is pale with scalloped margins (green arrows). | |
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Retrosternal Goitre Image 3a, 3b, 3c and 3d (Computed Tomography): The right lobe of the thyroid is considerably enlarged with retrosternal extension and deviation of the trachea to the left (arrows). There are a few mediastinal nodes which measure around 1cm in short axis diameter.
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Multinodular (Colloid) Goitre Image 4a: Total thyroidectomy showing a multinodular goitre with marked asymmetrical enlargement of the right lobe due to a massive dominant nodule. |
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Image 4b (H&E, x2.5): Histological section of a multinodular (colloid) goitre showing the usual features of variously sized, colloid-containing follicles lined by uniform epithelial cells, patchy areas of haemorrhage and fibrosis. | |
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Pathology images courtesy of PathWest Laboratory Medicine.