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Renal Cell Carcinoma Image 1 (Computed Tomography): Large right kidney mass with central necrosis consistent with renal cell carcinoma. There is tumour extension into the right renal vein (arrow).
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Renal Cell Carcinoma Image 2a: Nephrectomy showing a circumscribed and encapsulated renal cell carcinoma arising from the lower pole of the kidney. The cut surface shows a heterogenous appearance typical of malignancy with patchy areas of necrosis (blue arrow) and haemorrhage (red arrow). |
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Image 2b (H&E, x10): Histological section of a conventional clear cell renal cell carcinoma showing sheets and nests of malignant cells with intervening thin-walled vessels. The cells demonstrate irregular and hyperchromatic nuclei surrounded by abundant clear cytoplasm (clear cells). | |
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Pathology
images courtesy of PathWest Laboratory Medicine.