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Diagnostic Imaging Pathways - Suspected Primary Hyperparathyroidism

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Teaching Points

  • Imaging for pre-operative localisation of the parathyroid glands remains controversial although it is generally recommended for minimally invasive or unilateral neck surgery.
  • Ultrasound and Sestamibi scans are sensitive methods used as first line investigations, frequently in combination.
  • CT and MRI have the advantage of superior anatomical localisation but are usually reserved for equivocal or negative ultrasound and nuclear medicine studies.
  • Preoperative imaging is required for recurrent or persistent hyperparathyroidism to minimise the risks of repeat surgery and to maximise the chances of succesful treatment.

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