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Diagnostic Imaging Pathways - Primary Hyperaldosteronism

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Adrenal Adenoma

Image 1a, b and c (Computed Tomography): There is a 12mm sized rounded hypodense mass lesion noted in the right adrenal gland. There is marked contrast wash-out demonstrated in the lesion which is in keeping with adenoma.

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1d Click to view full size image   Image 1d (Adrenal Vein Sampling): A sample is taken from the left adrenal vein for analysis and comparison to that from the right renal vein.
       
2a Click to view full size image   Adrenocortical Adenoma Image 2a: Adrenalectomy specimen showing a typical adrenocortical adenoma forming a circumscribed and encapsulated mass with a homogenous yellow cut surface. Note the residual adrenal parenchyma at the periphery of the lesion (arrow).
2b Click to view full size image   Image 2b (H&E, x2.5) and 2c (H&E, x10): Histological section showing the pushing border between the adenoma and the surrounding parenchyma (arrows) At higher power, the cells form sheets and nests and exhibit uniform nuclei and clear cytoplasm due to their high lipid content.


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