Image 1a, b and c (Computed Tomography): There is a 12mm sized rounded hypodense mass lesion noted in the right adrenal gland.
There is marked contrast wash-out demonstrated in the lesion which is in keeping with adenoma.
1b
1c
1d
Image 1d (Adrenal Vein Sampling): A sample is taken from the left adrenal vein for analysis and comparison to that from the right renal vein.
2a
Adrenocortical Adenoma Image 2a: Adrenalectomy specimen showing a typical adrenocortical
adenoma forming a circumscribed and encapsulated mass with a homogenous
yellow cut surface. Note the residual adrenal parenchyma at the periphery of
the lesion (arrow).
2b
Image 2b (H&E, x2.5) and 2c (H&E, x10): Histological section showing the
pushing border between the adenoma and the surrounding parenchyma (arrows)
At higher power, the cells form sheets and nests and exhibit
uniform nuclei and clear cytoplasm due to their high lipid content.
2c
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Pathology
images courtesy of PathWest Laboratory Medicine.