Image 1a, b, c and d (Computed Tomography): The right lobe of the thyroid is considerably enlarged with retrosternal extension and deviation of the trachea to the left (arrows). There are a few mediastinal nodes which measure around 1cm in short axis diameter.
1b
1c
1d
2a
Multinodular (Colloid) Goitre
Image 2a: Total thyroidectomy showing a multinodular goitre with marked
asymmetrical enlargement of the right lobe due to a massive dominant nodule.
2b
Image 2b (H&E, x2.5): Histological section of a multinodular (colloid)
goitre showing the usual features of variously sized, colloid-containing
follicles lined by uniform epithelial cells, patchy areas of haemorrhage and
fibrosis.
2c
Image 2c (H&E, x10): Histological section of Graves' disease showing
hyperplastic follicles with infolding of the follicular epithelium to form
papillary projections (blue arrow). The colloid is pale with scalloped
margins (green arrows).
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Pathology
images courtesy of PathWest Laboratory Medicine.